Quinupristin/dalfopristin in Staphylococcus aureus endophthalmitis: a case report

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Metastatic Staphylococcus aureus endophthalmitis: a case report.

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Quinupristin/dalfopristin in Staphylococcus aureus endophthalmitis: a case report

INTRODUCTION The intravitreal injection of antibiotics remains the mainstay of therapy for postoperative endophthalmitis. Bacterial resistance, however, is still a pitfall in achieving an adequate response to treatment. Quinupristin/dalfopristin might be a feasible therapeutic option in these cases. CASE PRESENTATION A 55-year-old Hispanic man had endophthalmitis secondary to Staphylococcus a...

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Immune response to Staphylococcus aureus endophthalmitis in a rabbit model.

Staphylococcus aureus is an important cause of severe bacterial endophthalmitis. Both immunoglobulin (Ig) G and A antibody titers to ribitol teichoic acid (RTA), the major antigenic determinant of the S. aureus cell wall, were measured by an enzyme-linked immunosorbent assay in serum, tears, aqueous, and vitreous on days 3, 7, 10, 14, 21, and 30 after intravitreal injection of viable S. aureus ...

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Cytokine expression in a rat model of Staphylococcus aureus endophthalmitis.

PURPOSE To examine the ability of viable Staphylococcus aureus to induce the production of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, cytokine-induced neutrophil chemoattractant (CINC), and interferon (IFN)-gamma after intravitreal injection. METHODS Experimental rat eyes were injected with a 25-microl volume of approximately 80 colony-forming units of viable S. aureus; contro...

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Role of wall teichoic acids in Staphylococcus aureus endophthalmitis.

PURPOSE Wall teichoic acids (WTAs) are major polyanionic polymer components of the cell wall of Staphylococcus aureus. However, little is known about their role at the host-pathogen interface, especially in endophthalmitis. This study was designed to investigate the extent to which WTAs contribute to the pathogenicity of S. aureus in models of endophthalmitis and to determine whether there woul...

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ژورنال

عنوان ژورنال: Journal of Medical Case Reports

سال: 2011

ISSN: 1752-1947

DOI: 10.1186/1752-1947-5-130